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bioRxiv · 10.1101/2021.09.17.460764

Group size planning of breedings of gene-modified animals

Milchevskaya, V.·Bugnon, P.·ten Buren, E. B. J.·Brand, F.·Tresch, A.·Buch, T.
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Abstract

Animal breeding is time-consuming, costly, and affected by stochastic events related to Mendelian genetics, fertility, and litter size. Careful planning is mandatory to ensure a successful outcome using the least number of animals, hence adhering to the 3Rs of animal welfare. We have developed an R package, accessible also through an interactive website, that optimizes breeding design and provides a comprehensive report suitable for any breeder of genetically defined traits.

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Milchevskaya, V., Bugnon, P., ten Buren, E. B. J., Brand, F., Tresch, A., Buch, T.. 2021-09-20. Group size planning of breedings of gene-modified animals. https://doi.org/10.1101/2021.09.17.460764

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