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bioRxiv · 10.1101/2021.09.16.460692

Spatial working memory representations in human cortex are robust to a task-irrelevant interrupting stimulus

Abstract

Visual working memory (WM) enables the maintenance and manipulation of information no longer accessible in the visual world. Previous research has identified spatial WM representations in activation patterns in visual, parietal, and frontal cortex. In natural vision, the period between the encoding of information into WM and the time when it is used to guide behavior (the delay period) is rarely "empty", as is the case in most of the above laboratory experiments. In naturalistic conditions, eye movements, movement of the individual, and events in the environment result in visual signals which may overwrite or impair the fidelity of WM representations, especially in early sensory cortices. Here, we evaluated the extent to which a brief, irrelevant interrupting visual stimulus presented during a spatial WM delay period impaired behavioral performance and WM representation fidelity assayed using an image reconstruction technique (inverted encoding model). On each trial, participants (both sexes) viewed two target dots and were immediately post-cued to remember the precise spatial position of one dot. On 50% of trials, a brief interrupter stimulus appeared. While we observed strong transient univariate visual responses to the distracter stimulus, we saw no change in reconstructed neural WM representations under distraction, nor a change in behavioral performance on a continuous recall task. This suggests that spatial WM representations may be particularly robust to interference from incoming task-irrelevant visual information, perhaps related to their role in guiding movements.

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BibTeXRIS

Vu-Cheung, K., Ester, E. F., Sprague, T. C.. 2021-09-19. Spatial working memory representations in human cortex are robust to a task-irrelevant interrupting stimulus. https://doi.org/10.1101/2021.09.16.460692

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