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bioRxiv · 10.1101/2021.09.06.459169

PHIST: fast and accurate prediction of prokaryotichosts from metagenomic viral sequences

Zielezinski, A.·Deorowicz, S.·Gudys, A.
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Abstract

SummaryPHIST (Phage-Host Interaction Search Tool) predicts prokaryotic hosts of viruses from their genomic sequences. It improves host prediction accuracy at species level over current alignment-based tools (on average by 3 percentage points) as well as alignment-free and CRISPR-based tools (by 14-20 percentage points). PHIST is also two orders of magnitude faster than alignment-based tools making it suitable for metagenomics studies. Availability and implementationGNU-licensed C++ code wrapped in Python API available at: https://github.com/refresh-bio/phist Contactandrzej.zielezinski@amu.edu.pl, adam.gudys@polsl.pl Supplementary informationSupplementary data are available at publisher Web site.

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Zielezinski, A., Deorowicz, S., Gudys, A.. 2021-09-06. PHIST: fast and accurate prediction of prokaryotichosts from metagenomic viral sequences. https://doi.org/10.1101/2021.09.06.459169

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