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bioRxiv · 10.1101/2021.08.02.453487

NewWave: a scalable R/Bioconductor package for the dimensionality reduction and batch effect removal of single-cell RNA-seq data

Agostinis, F.·Romualdi, C.·Sales, G.·Risso, D.
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Abstract

SummaryWe present NewWave, a scalable R/Bioconductor package for the dimensionality reduction and batch effect removal of single-cell RNA sequencing data. To achieve scalability, NewWave uses mini-batch optimization and can work with out-of-memory data, enabling users to analyze datasets with millions of cells. Availability and implementationNewWave is implemented as an open-source R package available through the Bioconductor project at https://bioconductor.org/packages/NewWave/ Supplementary informationSupplementary data are available at Bioinformatics online.

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Agostinis, F., Romualdi, C., Sales, G., Risso, D.. 2021-08-03. NewWave: a scalable R/Bioconductor package for the dimensionality reduction and batch effect removal of single-cell RNA-seq data. https://doi.org/10.1101/2021.08.02.453487

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