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bioRxiv · 10.1101/2021.07.29.454382

MOSGA 2: Comparative genomics and validation tools

Martin, R.·Dressler, H.·Hattab, G.·Hackl, T.·Fischer, M. G.·Heider, D.
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Abstract

Due to the highly growing number of available genomic information, the need for accessible and easy-to-use analysis tools is increasing. To facilitate eukaryotic genome annotations, we created MOSGA. In this work, we show how MOSGA 2 is developed by including several advanced analyses for genomic data. Since the genomic data quality greatly impacts the annotation quality, we included multiple tools to validate and ensure high-quality user-submitted genome assemblies. Moreover, thanks to the integration of comparative genomics methods, users can benefit from a broader genomic view by analyzing multiple genomic data sets simultaneously. Further, we demonstrate the new functionalities of MOSGA 2 by different use-cases and practical examples. MOSGA 2 extends the already established application to the quality control of the genomic data and inte-grates and analyzes multiple genomes in a larger context, e.g., by phylogenetics.

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Martin, R., Dressler, H., Hattab, G., Hackl, T., Fischer, M. G., Heider, D.. 2021-07-30. MOSGA 2: Comparative genomics and validation tools. https://doi.org/10.1101/2021.07.29.454382

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