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bioRxiv · 10.1101/2021.07.06.451269

Spontaneous pauses in firing of external pallidum neurons are associated with exploratory behavior

Kaplan, A.·Mizrahi-Kliger, A. D.·Rappel, P.·Iskhakova, L.·Fonar, G.·Israel, Z.·Bergman, H.
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Abstract

Spontaneous pauses in firing are the hallmark of external pallidum (GPe) neurons. However, their role in the basal ganglia (BG) network remains unknown. Pupil size and saccades have been linked to attention and exploration. Here, we show that pauses are associated with dilated pupils and increased saccade rate. Our results suggest that pauses are a powerful mechanism by which the GPe may influence BG downstream structures and affect behavioral output.

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Kaplan, A., Mizrahi-Kliger, A. D., Rappel, P., Iskhakova, L., Fonar, G., Israel, Z., Bergman, H.. 2021-07-07. Spontaneous pauses in firing of external pallidum neurons are associated with exploratory behavior. https://doi.org/10.1101/2021.07.06.451269

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