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bioRxiv · 10.1101/2021.05.19.444876

Circularly permuted LOV domain as an engineering module for optogenetic tools

Wang, W.·Geng, L.·Shen, J.
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Abstract

We re-engineered a commonly-used light-sensing protein, LOV domain, using a circular permutation strategy to allow photoswitchable control of the C-terminus of a peptide. We demonstrate that the use of circularly permuted LOV domain on its own or together with the original LOV could expand the engineering capabilities of optogenetic tools.

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Wang, W., Geng, L., Shen, J.. 2021-05-19. Circularly permuted LOV domain as an engineering module for optogenetic tools. https://doi.org/10.1101/2021.05.19.444876

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