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bioRxiv · 10.1101/2021.04.13.439670

UCell: robust and scalable single-cell gene signature scoring

Andreatta, M.·Carmona, S. J.
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Abstract

UCell is an R package for evaluating gene signatures in single-cell datasets. UCell signature scores, based on the Mann-Whitney U statistic, are robust to dataset size and heterogeneity, and their calculation demands less computing time and memory than other available methods, enabling the processing of large datasets in a few minutes even on machines with limited computing power. UCell can be applied to any single-cell data matrix, and includes functions to directly interact with Seurat objects. The UCell package and documentation are available on GitHub at https://github.com/carmonalab/UCell

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Andreatta, M., Carmona, S. J.. 2021-04-14. UCell: robust and scalable single-cell gene signature scoring. https://doi.org/10.1101/2021.04.13.439670

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