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bioRxiv · 10.1101/2021.04.01.437964

Regimes and mechanisms of transient amplification in abstract and biological networks

Christodoulou, G.·Vogels, T. P.·Agnes, E. J.
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Abstract

We use upper triangular matrices as abstract representations of neuronal networks and directly manipulate their eigenspectra and non-normality to explore different regimes of transient amplification. Counter-intuitively, manipulating the imaginary distribution can lead to highly amplifying regimes. This is noteworthy, because biological networks are constrained by Dales law and the non-existence of neuronal self-loops, limiting the range of manipulations in the real dimension. Within these constraints we can further manipulate transient amplification by controlling global inhibition.

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Christodoulou, G., Vogels, T. P., Agnes, E. J.. 2021-04-02. Regimes and mechanisms of transient amplification in abstract and biological networks. https://doi.org/10.1101/2021.04.01.437964

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