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bioRxiv · 10.1101/2021.02.08.430198

RNA fragment assembly with experimental restraints

Chojnowski, G.·Zaborowski, R.·Magnus, M.·Bujnicki, J. M.
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Abstract

We present RNA Masonry, a computer program and a web service for a fully automated assembly of RNA fragments into geometrically plausible models fulfilling user-provided secondary structure constraints and restraints on tertiary contacts and Small Angle X-ray Scattering (SAXS) data. We illustrate the method description with its recent application to structural studies of viral RNAs with SAXS restraints. The program web server is available at http://iimcb.genesilico.pl/rnamasonry. Contactgchojnowski@embl-hamburg.de

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Chojnowski, G., Zaborowski, R., Magnus, M., Bujnicki, J. M.. 2021-02-09. RNA fragment assembly with experimental restraints. https://doi.org/10.1101/2021.02.08.430198

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