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bioRxiv · 10.1101/2020.12.23.424122

The Prevalence of the Val66Met Polymorphism in Musicians: Possible Evidence for Compensatory Neuroplasticity from a pilot study.

Henechowicz, T. L.·Chen, J. L.·Cohen, L. G.·Thaut, M. H.
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Abstract

It has been reported that MET carriers may express deficits in motor learning and neuroplasticity, possibly deterring musicianship. Here, we compared the prevalence of the Val66Met Brain-derived Neurotrophic Factor single nucleotide polymorphism (rs6265) in a sample of musicians (N=50) and an ethnically matched subset from the 1000 Human Genome Project (N-424). We report no differences in genotype or allele frequencies. Results are consistent with the view that hypothesized Met-dependent deficits in neuroplasticity are either mild or can be overcome by long-term practice.

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Henechowicz, T. L., Chen, J. L., Cohen, L. G., Thaut, M. H.. 2020-12-23. The Prevalence of the Val66Met Polymorphism in Musicians: Possible Evidence for Compensatory Neuroplasticity from a pilot study.. https://doi.org/10.1101/2020.12.23.424122

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