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bioRxiv · 10.1101/2020.10.31.363291

Development of a Novel Index to Characterise Arterial Dynamics Using Ultrasound Imaging

Ward, J.·Cheng, X.·Xiao, Y.·Lapolla, P.·Chandrashekar, A.·Handa, A.·Cleveland, R.·Lee, R.
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Abstract

Abdominal aortic aneurysms (AAA) are associated with systemic inflammation and endothelial dysfunction. We previously reported flow mediated dilatation (FMD) of the brachial artery as a predictor of AAA growth. We hence hypothesised that other physical characteristics of the brachial artery correlate with AAA growth. Using a prospectively cohort of AAA patients, we devised a brachial artery relaxation index (BARI) and examined its role as a biomarker for AAA growth. However, no correlation between BARI and future aneurysm growth was observed (p=0.5). Therefore, our investigations did not substantiate the hypothesis that other physical characteristics of the brachial artery predicts AAA growth.

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Ward, J., Cheng, X., Xiao, Y., Lapolla, P., Chandrashekar, A., Handa, A., Cleveland, R., Lee, R.. 2020-11-02. Development of a Novel Index to Characterise Arterial Dynamics Using Ultrasound Imaging. https://doi.org/10.1101/2020.10.31.363291

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