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bioRxiv · 10.1101/2020.07.02.184242

Modeling of Nano-carriers for Vascular-targeted Delivery for Blood Clots Treatment

Eltayeb, M.·Yahya, I.
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Abstract

Nanoparticles have become one of the emerging and promising technologies that revolutionized the medical fields future on which has received much attention from the scientific community and researchers. Nanotechnology-based targeted drug delivery has a high capacity for loading large amounts of anticoagulants drug to dissolve clots in a safe manner without affecting healthy blood vessels. This paper seeks to provide a better understanding of both the anticoagulant drug release process and the coagulation eliminating process by simulating each process using chemical reaction engineering, moving mesh, and convection-diffusion equation modules. This study adds to a growing corpus of research showing that nanotechnology empowers in treating blood clots within 2-4 hours. In addition, these results cast a new light on a better understanding of the anticoagulation drug diffusion from both spheres and multiply-twinned nanoparticles besides the reduction of clots growth and how it dissolved over time.

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Eltayeb, M., Yahya, I.. 2020-07-02. Modeling of Nano-carriers for Vascular-targeted Delivery for Blood Clots Treatment. https://doi.org/10.1101/2020.07.02.184242

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