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bioRxiv · 10.1101/2020.05.25.115550

UPhyloplot2: Visualizing Phylogenetic Trees from Single-Cell RNA-seq Data

Kurtenbach, S.·Rodriguez, D. A.·Durante, M. A.·Harbour, J. W.
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Abstract

Recent advances in single cell sequencing technologies allow for greater resolution in assessing tumor clonality using chromosome copy number variations (CNVs), which can be inferred from single cell RNA-seq (scRNA-seq) data using applications such as inferCNV. Inferences regarding tumor clonality are frequently visualized using phylogenetic plots, which previously required time-consuming and tedious manual analysis. Here, we present UPhyloplot2, a python script that generates phylogenetic plots directly from inferCNV output files. The tool is publicly available at https://github.com/harbourlab/UPhyloplot2/.

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Kurtenbach, S., Rodriguez, D. A., Durante, M. A., Harbour, J. W.. 2020-05-28. UPhyloplot2: Visualizing Phylogenetic Trees from Single-Cell RNA-seq Data. https://doi.org/10.1101/2020.05.25.115550

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