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bioRxiv · 10.1101/2020.03.09.984856

Tilorone: A Broad-Spectrum Antiviral For Emerging Viruses

Ekins, S.·Madrid, P.
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Abstract

Tilorone is a 50-year-old synthetic small-molecule compound with antiviral activity that is proposed to induce interferon after oral administration. This drug is used as a broad-spectrum antiviral in several countries of the Russian Federation. We have recently described activity in vitro and in vivo against the Ebola Virus. After a broad screening of additional viruses, we now describe in vitro activity against Chikungunya virus (CHIK) and Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV).

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Ekins, S., Madrid, P.. 2020-03-11. Tilorone: A Broad-Spectrum Antiviral For Emerging Viruses. https://doi.org/10.1101/2020.03.09.984856

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