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bioRxiv · 10.1101/2020.03.08.981910

Chromosight: A computer vision program for pattern detection in chromosome contact maps

Matthey-Doret, C.·Baudry, L.·Breuer, A.·Guiglielmoni, N.·Moreau, P.·Vigouroux, A.·Montagne, R.·Scolari, V.·Politis, L.·Meot, A.·Oriol, E.·Chanut, P.-H.·Campeas, A.·Jean, E.·Koszul, R.·Cournac, A.
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Abstract

Chromosomes of all species studied so far display a variety of higher order organizational features such as domains or loops often associated to biological functions and visible on Hi-C contact maps. We developed Chromosight, an algorithm inspired from computer vision that can detect patterns in Hi-C maps. Chromosight has greater sensitivity than existing methods, while being faster and applicable to any type of genomes, including bacteria, viruses, yeasts and mammals. Code and documentation: https://github.com/koszullab/chromosight

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Matthey-Doret, C., Baudry, L., Breuer, A., Guiglielmoni, N., Moreau, P., Vigouroux, A., Montagne, R., Scolari, V., Politis, L., Meot, A., Oriol, E., Chanut, P.-H., Campeas, A., Jean, E., Koszul, R., Cournac, A.. 2020-03-08. Chromosight: A computer vision program for pattern detection in chromosome contact maps. https://doi.org/10.1101/2020.03.08.981910

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