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bioRxiv · 10.1101/2020.02.07.938928

In Vitro Assessment of Antioxidant activity, Antimicrobial, and cytotoxicity of ultrasound-assisted acetone extracts of Plectranthus amboinicus

Ye, X.
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Abstract

The bacteriostatic, antioxidant and cytotoxic activities of a series of Plectranthus amboinicus were determined. The bacteriostatic performance of Plectranthus amboinicus was evaluated by evaluating the bacteriostatic effect of 10 mg/mL on Gram-positive and Gram-negative bacteria and yeasts. The antioxidant activity of Plectranthus amboinicus was analyzed by DPPH method, and the results showed that it had strong ability of scavenging free radicals. In addition, the general toxicity of Plectranthus amboinicus was evaluated in the Artemia model, and the results showed that the toxicity value was not significant. In turn, through the evaluation of cell viability, all extracts were found to be non-toxic in the concentration range of 0-10 g/mL in Vero-E6 and 786-O cells. The tested samples have encouraging antibacterial and antioxidant properties, which represents the plants role in designing new drugs to treat infectious diseases.

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Ye, X.. 2020-02-07. In Vitro Assessment of Antioxidant activity, Antimicrobial, and cytotoxicity of ultrasound-assisted acetone extracts of Plectranthus amboinicus. https://doi.org/10.1101/2020.02.07.938928

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