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bioRxiv · 10.1101/2019.12.19.882092

Robust Stability of Multicomponent Membranes: theRole of Glycolipids

Chen, Y.·Doelman, A.·Promislow, K.·Veerman, F.
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Abstract

We present the multicomponent functionalized free energies that characterize the low-energy packings of amphiphilic molecules within a membrane through a correspondence to connecting orbits within a reduced dynamical system. To each connecting orbits we associate a manifold of low energy membrane-type configurations parameterized by a large class of admissible interfaces. The normal coercivity of the manifolds is established through criteria depending solely on the structure of the associated connecting orbit. We present a class of examples that arise naturally from geometric singular perturbation techniques, focusing on a model that characterizes the stabilizing role of cholesterol-like glycolipids within phospholipid membranes.

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Chen, Y., Doelman, A., Promislow, K., Veerman, F.. 2019-12-19. Robust Stability of Multicomponent Membranes: theRole of Glycolipids. https://doi.org/10.1101/2019.12.19.882092

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