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bioRxiv · 10.1101/201400

Antenatal Screening for Group B Streptococcus in the Setting of Preterm Premature Rupture of Membranes: Empiric versus Culture-based Prophylaxis

Mithal, L. B.·Shah, N.·Romanova, A.·Miller, E. S.
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Abstract

Introduction Introduction Methods Results Discussion References Group B streptococcus (GBS) bacteria colonizes the genital tract in 10-30% of pregnant women.1,2 GBS colonization during pregnancy is the primary risk factor for neonatal GBS infection with its accompanying risks of significant infant morbidity and mortality.3-5 Over the last several decades, intrapartum intravenous administration of antibiotics to women at risk for transmitting GBS has greatly reduced neonatal disease.3,6,7 Current CDC guidelines recommend routine screening for GBS at 35-37 weeks gestation and subsequent administration of intrapartum antibiotics if the GBS screen is positive (universal culture-base ...

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Mithal, L. B., Shah, N., Romanova, A., Miller, E. S.. 2017-10-12. Antenatal Screening for Group B Streptococcus in the Setting of Preterm Premature Rupture of Membranes: Empiric versus Culture-based Prophylaxis. https://doi.org/10.1101/201400

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