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bioRxiv · 10.1101/153379

Hippocampal Spike-Timing Correlations Lead to Hexagonal Grid Fields

Monsalve-Mercado, M. M.·Leibold, C.
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Abstract

Space is represented in the mammalian brain by the activity of hippocampal place cells as well as in their spike-timing correlations. Here we propose a theory how this temporal code is transformed to spatial firing rate patterns via spike-timing-dependent synaptic plasticity. The resulting dynamics of synaptic weights resembles well-known pattern formation models in which a lateral inhibition mechanism gives rise to a Turing instability. We identify parameter regimes in which hexagonal firing patterns develop as they have been found in medial entorhinal cortex.

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Monsalve-Mercado, M. M., Leibold, C.. 2017-06-21. Hippocampal Spike-Timing Correlations Lead to Hexagonal Grid Fields. https://doi.org/10.1101/153379

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