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bioRxiv · 10.1101/099895

CRISPR-RT: A web service for designing CRISPR-C2c2 crRNA with improved target specificity

Zhu, H.·Richmond, E.·Liang, C.
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Abstract

CRISPR-Cas systems have been successfully applied in genome editing. Recently, the CRISPR-C2c2 system has been reported as a tool for RNA editing. Here we describe CRISPR-RT (CRISPR RNA-Targeting), the first web service to help biologists design the crRNA with improved target specificity for the CRISPR-C2c2 system. CRISPR-RT allows users to set up a wide range of parameters, making it highly flexible for current and future research in CRISPR-based RNA editing. CRISPR-RT covers major model organisms and can be easily extended to cover other species. CRISPR-RT will empower researchers in RNA editing. It is available at http://bioinfolab.miamioh.edu/CRISPR-RT.

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Zhu, H., Richmond, E., Liang, C.. 2017-01-12. CRISPR-RT: A web service for designing CRISPR-C2c2 crRNA with improved target specificity. https://doi.org/10.1101/099895

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