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bioRxiv · 10.1101/089177

Constructing high-density linkage maps with MapDisto 2.0

Heffelfinger, C.·Fragoso, C. A.·Lorieux, M.
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Abstract

We present the second major release of MapDisto, a multi-platform, user-friendly computer program for constructing genetic linkage maps of experimental populations. This version includes several new major features: (i) handling of very large genotyping datasets like the ones generated by genotyping-by-sequencing (GBS); (ii) direct importation and conversion of Variant Call Format (VCF) files; (iii) detection of linkage, i.e. construction of linkage groups in case of segregation distortion; (iv) data imputation on VCF files using a new approach, called LB-Impute. These features operate through inclusion of new Java modules that are installed and used transparently by MapDisto; (v) QTL detection via a new R/qtl graphical interface.\n\nThe program is available free of charge at mapdisto.free.fr.

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Heffelfinger, C., Fragoso, C. A., Lorieux, M.. 2016-11-22. Constructing high-density linkage maps with MapDisto 2.0. https://doi.org/10.1101/089177

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