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bioRxiv · 10.1101/081992

CancerGD: a resource for identifying and interpreting genetic dependencies in cancer

Bridgett, S.·Campbell, J.·Lord, C. J.·Ryan, C. J.
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Abstract

Genes whose function is selectively essential in the presence of cancer associated genetic aberrations represent promising targets for the development of precision therapeutics. Here we present CancerGD (www.cancergd.org), a resource that integrates genotypic profiling with large-scale loss-of-function genetic screens in tumor cell lines to identify such genetic dependencies. CancerGD provides tools for searching, visualizing, and interpreting these genetic dependencies through the integration of functional interaction networks.

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Bridgett, S., Campbell, J., Lord, C. J., Ryan, C. J.. 2016-10-26. CancerGD: a resource for identifying and interpreting genetic dependencies in cancer. https://doi.org/10.1101/081992

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