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bioRxiv · 10.1101/076927

dbOTU3: A new implementation of distribution-based OTU calling

Scott W Olesen·Claire Duvallet·Eric J Alm
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Abstract

1Distribution-based operational taxonomic unit-calling (dbOTU) improves on other approaches by incorporating information about the input sequences distribution across samples. Previous implementations of dbOTU presented challenges for users. Here we introduce and evaluate a new implementation of dbOTU that is faster and more user-friendly. We show that this new implementation has theoretical and practical improvements over previous implementations of dbOTU, making the algorithm more accessible to microbial ecology and biomedical researchers.

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Scott W Olesen, Claire Duvallet, Eric J Alm. 2016-09-22. dbOTU3: A new implementation of distribution-based OTU calling. https://doi.org/10.1101/076927

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