GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome

Boris Simovski; Daniel Vodak; Sveinung Gundersen; Diana Domanska; Abdulrahman Azab; Lars Holden; Marit Holden; Ivar Grytten; Knut Dagestad Rand; Finn Drablos; Morten Johansen; Antonio Mora; Christin Lund-Andersen; Bastian Fromm; Ragnhild Eskeland; Odd Stokke Gabrielsen; Sigve Nakken; Mads Bengtsen; Alexander Johan Nederbragt; Hildur Sif Thorarensen; Johannes Andreas Akse; Ingrid Glad; Eivind Hovig; Geir Kjetil Sandve

doi:10.1101/067561

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bioRxiv · 10.1101/067561

GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome

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Abstract

Genome-wide, cell-type-specific profiles are being systematically generated for numerous genomic and epigenomic features. There is, however, no universally applicable analytical methodology for such data. We present GSuite HyperBrowser, the first comprehensive solution for integrative analysis of dataset collections across the genome and epigenome. The GSuite HyperBrowser is an open-source system for streamlined acquisition and customizable statistical analysis of large collections of genome-wide datasets. The system is based on new computational and statistical methodologies that permit comparative and confirmatory analyses across multiple disparate data sources. Expert guidance and reproducibility are facilitated via a Galaxy-based web-interface. The software is available at https://hyperbrowser.uio.no/gsuite

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Boris Simovski, Daniel Vodak, Sveinung Gundersen, Diana Domanska, Abdulrahman Azab, Lars Holden, Marit Holden, Ivar Grytten, Knut Dagestad Rand, Finn Drablos, Morten Johansen, Antonio Mora, Christin Lund-Andersen, Bastian Fromm, Ragnhild Eskeland, Odd Stokke Gabrielsen, Sigve Nakken, Mads Bengtsen, Alexander Johan Nederbragt, Hildur Sif Thorarensen, Johannes Andreas Akse, Ingrid Glad, Eivind Hovig, Geir Kjetil Sandve. 2016-08-03. GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome. https://doi.org/10.1101/067561

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