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bioRxiv · 10.1101/016394

Measuring forces and stresses in situ in living tissues

Forces-in-tissue workshop participants
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Abstract

Development, homeostasis and regeneration of tissues result from the interaction of genetics and mechanics. Kinematics and rheology are two main classes of measurements respectively providing deformations and mechanical properties of a material. They are now applied to living tissues and have contributed to the better understanding of their mechanics. Due to the complexity of living tissues, however, a third class of mechanical measurements, that of in situ forces and stresses, appears to be increasingly important to elaborate realistic models of tissue mechanics. We review here several emerging techniques of this class, their fields of applications, their advantages and limitations, and their validations. We argue that they will strongly impact on our understanding of developmental biology in the near future.

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Forces-in-tissue workshop participants. 2015-03-11. Measuring forces and stresses in situ in living tissues. https://doi.org/10.1101/016394

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