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bioRxiv · 10.1101/000661

Natural Allelic Variations of Xenobiotic Enzymes Pleiotropically Affect Sexual Dimorphism in Oryzias latipes

Takafumi Katsumura·Shoji Oda·Shigeki Nakagome·Tsunehiko Hanihara·Hiroshi Kataoka·Hiroshi Mitani·Shoji Kawamura·Hiroki Oota
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Abstract

Summary Summary Highlights Results and Discussion Accession Numbers Reference Sexual dimorphisms, which are phenotypic differences between males and females, are driven by sexual selection [1, 2]. Interestingly, sexually selected traits show geographic variations within species despite strong directional selective pressures [3, 4]. However, genetic factors that regulate varied sexual differences remain unknown. In this study, we show that polymorphisms in cytochrome P450 (CYP) 1B1, which encodes a xenobiotic-metabolising enzyme, are associated with local differences of sexual dimorphisms in the anal fin morphology of medaka fish (Oryzias latipes). High and low activity CYP1B1 alleles increased and decreased differences in anal fin sizes ...

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Takafumi Katsumura, Shoji Oda, Shigeki Nakagome, Tsunehiko Hanihara, Hiroshi Kataoka, Hiroshi Mitani, Shoji Kawamura, Hiroki Oota. 2013-11-19. Natural Allelic Variations of Xenobiotic Enzymes Pleiotropically Affect Sexual Dimorphism in Oryzias latipes. https://doi.org/10.1101/000661

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