TY - RPRT TI - Topoisomerase-mediated resolution of negative DNA supercoiling sustains human transcription and gene activation AU - Lyu, J. AU - Ahmed, A. AU - Biswas, I. AU - Li, S. AU - Chen, C. PY - 2026 DO - 10.64898/2026.09.30.755832 UR - https://www.biorxiv.org/content/10.64898/2026.09.30.755832v1 ID - 10.64898/2026.09.30.755832 ER -