TY - RPRT TI - Pair-complete structural gating enables Pareto optimization of de novo cyclic peptides with preserved binding geometry and improved developability AU - Hou, Y. AU - Zhang, Y. AU - Liu, Z. AU - Peng, X. AU - Yusupujiang, M. AU - Xu, Y. AU - Hu, J. AU - Yang, S. PY - 2026 DO - 10.64898/2026.09.24.754053 UR - https://www.biorxiv.org/content/10.64898/2026.09.24.754053v1 ID - 10.64898/2026.09.24.754053 ER -