@misc{indiciae3a226eb694ce, title = {CatESO: Differentiable Enzyme Sequence Optimization Guided by Substrate-Aware kcat Prediction}, author = {Gan, Z. and Xu, Y. and Xu, J. and Wu, Z. and Huang, J. and Yin, J. and Chen, G. and Zhang, J. Z. H.}, year = {2026}, doi = {10.64898/2026.07.04.736506}, url = {https://www.biorxiv.org/content/10.64898/2026.07.04.736506v1}, note = {Source identifier: 10.64898/2026.07.04.736506} }