@misc{indiciae211feb6f961b, title = {From hotspot dependence to distributed robustness in resistance-aware lead optimization}, author = {Wang, Y. and Xiao, B. and Kang, J. and Cui, H. and Fu, Y. and Li, W. and Perea, S. E. and Han, W.}, year = {2026}, doi = {10.64898/2026.06.16.732538}, url = {https://www.biorxiv.org/content/10.64898/2026.06.16.732538v1}, note = {Source identifier: 10.64898/2026.06.16.732538} }