TY - RPRT TI - Combining high-resolution AFM with MD simulations shows that DNA supercoiling induces kinks and defects that enhance flexibility and recognition. AU - Pyne, A. L. B. AU - Noy, A. AU - Main, K. AU - Velasco-Berrelleza, V. AU - Piperakis, M. M. AU - Mitchenhall, L. A. AU - Cugliandolo, F. M. AU - Beton, J. G. AU - Stevenson, C. E. M. AU - Hoogenboom, B. W. AU - Bates, A. D. AU - Maxwell, A. AU - Harris, S. A. PY - 2019 DO - 10.1101/863423 UR - https://www.biorxiv.org/content/10.1101/863423v1 ID - 10.1101/863423 ER -