TY - RPRT TI - High-order epistasis in catalytic power of dihydrofolate reductase gives rise to a rugged fitness landscape in the presence of trimethoprim selection AU - Tamer, Y. T. AU - Gaszek, I. K. AU - Abdizadeh, H. AU - Batur, T. AU - Reynolds, K. AU - Atilgan, A. R. AU - Atilgan, C. AU - Toprak, E. PY - 2018 DO - 10.1101/398065 UR - https://www.biorxiv.org/content/10.1101/398065v1 ID - 10.1101/398065 ER -