@misc{indiciae95b0d3ddc1f9, title = {Modeling genome-wide evolution of catalytic turnover rates: Strong epistasis shaped modern enzyme kinetics}, author = {Heckmann, D. and Zielinski, D. C. and Palsson, B. O.}, year = {2018}, doi = {10.1101/318972}, url = {https://www.biorxiv.org/content/10.1101/318972v1}, note = {Source identifier: 10.1101/318972} }