TY - RPRT TI - Hypercholesterolaemia promotes epigenetic memory in hematopoietic stem cells that persists after lipid lowering and causes systemic immunometabolic dysfunction mediated by macrophage metabolic reprogramming AU - Purvis, G. S. D. AU - Jiang, J. AU - Hiron, T. K. AU - Simoglou Karali, C. AU - Baxter, M. AU - Li, R. AU - Vijjhalwar, R. AU - Diotallevi, M. AU - Draycott, S. A. V. AU - Chuaiphichai, S. AU - Douglas, G. AU - McNeill, E. AU - Mead, A. J. AU - Greaves, D. R. AU - O Callaghan, C. A. AU - Channon, K. PY - 2025 DO - 10.1101/2025.09.15.676283 UR - https://www.biorxiv.org/content/10.1101/2025.09.15.676283v1 ID - 10.1101/2025.09.15.676283 ER -