TY - RPRT TI - Molecular dynamic simulation reveals E484K mutation enhances spike RBD-ACE2 affinity and the combination of E484K, K417N and N501Y mutations (501Y.V2 variant) induces conformational change greater than N501Y mutant alone, potentially resulting in an escape mutant AU - Nelson, G. AU - Buzko, O. AU - Spilman, P. R. AU - Niazi, K. AU - Rabizadeh, S. AU - Soon-Shiong, P. R. PY - 2021 DO - 10.1101/2021.01.13.426558 UR - https://www.biorxiv.org/content/10.1101/2021.01.13.426558v1 ID - 10.1101/2021.01.13.426558 ER -