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piana, m.

Publications and source records attributed to piana, m..

2 recordsLinked to original sources

On the asymptotic equivalence between the Radon and the Hough transforms of digital images

Although characterized by different mathematical definitions, both the Radon and the Hough transforms ultimately take an image as input and provide, as output, functions defined on a preassigned parameter space, i.e., the so-called either Radon or Hough sinograms. The parameters in these two spaces describe a family of curves, which represent either the integration domains considered in the Radon transform, or the kind of curves to be detected by the Hough transform.\n\nIt is heuristically known that the Hough sinogram converges to the corresponding Radon sinogram when the discretization step in the parameter space tends to zero. By considering generalized functions in multi-dimensional setting, in this paper we give an analytical proof of this heuristic rationale when the input grayscale digital image is described as a set of grayscale points, that is, as a sum of weighted Dirac delta functions. On these grounds, we also show that this asymptotic equivalence may have a valuable impact on the image reconstruction problem of inverting the Radon sinogram recorded by a medical imaging scanner.

bioengineering↗

The role of the endoplasmic reticulum in in vivo cancer FDG kinetics

A very recent result obtained by means of an in vitro experiment with cancer cultured cells has configured the endoplasmic reticulum as the preferential site for the accumulation of 2-deoxy-2-[18F]fluoro-D-glucose (FDG). Such a result is coherent with cell biochemistry and is made more significant by the fact that reticular accumulation rate of FDG is dependent upon extracellular glucose availability. The objective of the present paper was to confirm this result in vivo, using small animal models of CT26 cancer tissues. Specifically, assuming that the endoplasmic reticulum plays a specific functional role in the framework of a three-compartment model for FDG kinetics, we are able to explain positron emission tomography dynamic data in a more reliable way than by means of a standard Sokoloff two-compartment system. This result is made more solid from a computational viewpoint by means of some identifiability considerations based on a mathematical analysis of the compartmental equations.

cancer biology↗