Biology subjects

Wiener, J.

Publications and source records attributed to Wiener, J..

3 recordsLinked to original sources

bioRxiv2026

Path Integration and Spatial Updating Recruit Distinct Cognitive-Neural Mechanisms in Humans

Path integration and spatial updating refer to the integration of self-motion information during navigation to update ones start location and the positions of other locations, respectively. Even though path integration has been described as a fundamental process whose output may serve as a building block for other navigational computations like spatial updating, the exact relationship between path integration and spatial updating is unknown. Here we addressed this question with an eye-tracking behavioral experiment and a subsequent fMRI study. Despite experiencing identical self-motion cues, participants showed differential eye fixation patterns and responded more quickly during spatial updating than during path integration, casting doubt on the fundamental role of path integration. Neuroimaging results showed that the precuneus and the dorsal premotor cortex were more activated during spatial updating, but the precuneus had stronger functional connectivity with the thalamus and the frontal cortex during path integration. Further supporting this dissociation, the two tasks invoked distinct brain-wide inter-regional functional networks. Together, the combined findings of both experiments suggest that spatial updating and path integration are dissociable navigation processes supported by distinct behavioral and neural mechanisms, rather than one process operating on the basis of the other.

neuroscience↗

bioRxiv2024

Predicting real-world navigation performance from a virtual navigation task in older adults

Virtual reality environments presented on tablets and smartphones offer a novel way of measuring navigation skill and predicting real-world navigation problems. The extent to which such virtual tests are effective at predicting navigation in older populations remains unclear. We compared the performance of 20 older participants (54-74 years old) in wayfinding tasks in a real-world environment in London, UK, and in similar tasks designed in a mobile app-based test of navigation (Sea Hero Quest). In a previous study with young participants (18-35 years old), we were able to predict navigation performance in real-world tasks in London and Paris using this mobile app. We find that for the older cohort, virtual navigation performance predicts real-world performance for medium difficulty, but not for the easy or difficult environments. While the younger sample outperformed the older sample in the virtual task, this was not the case in the real-world task, which conflicts with the dominant view of a decline in navigation ability with age. Self-reports identifying compensatory skills and further analysis of our participants scores in the Montreal Cognitive Assessment and in the Navigation Strategy Questionnaire help give insights into the higher performance in the real world. Overall, our study supports the utility of using digital tests of spatial cognition in older age groups, while carefully adapting the task difficulty to the population.

animal behavior and cognition↗

bioRxiv2017

Global determinants of navigation ability

Countries vary in their geographical and cultural properties. Only a few studies have explored how such variations influence how humans navigate or reason about space [1-7]. We predicted that these variations impact human cognition, resulting in an organized spatial distribution of cognition at a planetary-wide scale. To test this hypothesis we developed a mobile-app-based cognitive task, measuring non-verbal spatial navigation ability in more than 2.5 million people, sampling populations in every nation state. We focused on spatial navigation due to its universal requirement across cultures. Using a clustering approach, we find that navigation ability is clustered into five distinct, yet geographically related, groups of countries. Specifically, the economic wealth of a nation was predictive of the average navigation ability of its inhabitants, and gender inequality was predictive of the size of performance difference between males and females. Thus, cognitive abilities, at least for spatial navigation, are clustered according to economic wealth and gender inequalities globally, which has significant implications for cross-cultural studies and multi-centre clinical trials using cognitive testing.

neuroscience↗