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Biology subjects

Wallis, T. S.

Publications and source records attributed to Wallis, T. S..

2 recordsLinked to original sources

Predictive visual uncertainty around moving trajectories influences causality judgments in launching displays

Michottes "launching displays" are animations of collision-like interactions between two objects that elicit a stable and robust impression that one object, the launcher, caused another object, the target, to move. Although it is well-known that unexpected disruptions of movement continuation between launcher and target decrease causal impressions in centre-to-centre collisions, the role of observers visual uncertainty around predicted moving trajectories remains relatively unexplored. In this work, we (1) assess observers uncertainty around post-collision moving angles in a trajectory prediction task and (2) collect their causal impression in a causality rating task. In the latter task, observers viewed centre-to-centre collisions with different levels of movement continuity between the launcher and the target disc. By presenting different launch orientations, we exploited the well-known oblique effect to vary trajectory prediction uncertainty within individuals. If observers rely on their trajectory predictions to rate the causality of the collision, we expect their accuracy in (1) to have a systematic influence on their causality rating in (2). We replicate previous findings that observers report stronger causal impressions in trials where the target and the launcher move in the same direction and weaker causal impressions for collisions where the target and the launcher moving trajectory deviated. Furthermore, causality ratings were on average higher for oblique compared to cardinal launch directions, implying that increased sensory uncertainty induces a stronger causal impression. We hope this work will inspire deeper empirical assessments and computational models describing the role of sensory uncertainty and predictive processes in shaping subjective impressions of causality.

animal behavior and cognition↗

Genomic tailoring of autogenous poultry vaccines to reduce Campylobacter from farm to fork

Campylobacter is a leading cause of food-borne gastroenteritis worldwide, linked to the consumption of contaminated poultry meat. Targeting this pathogen at source, vaccines for poultry can provide short term caecal reductions in Campylobacter numbers in the chicken intestine. However, this approach is unlikely to reduce Campylobacter in the food chain or human incidence. This is likely as vaccines typically target only a subset of the high strain diversity circulating among chicken flocks and rapid evolution diminishes vaccine efficacy over time. To address this, we used a genomic approach to develop a whole-cell autogenous vaccine targeting isolates harbouring genes linked to survival outside of the host. We hyper-immunised a whole major UK breeder farm to passively target offspring colonisation using maternally-derived antibody. Monitoring progeny, broiler flocks revealed a near-complete shift in the post-vaccination Campylobacter population with a [~]50% reduction in isolates harbouring extra-intestinal survival genes and a significant reduction of Campylobacter cells surviving on the surface of meat. Based on these findings, we developed a logistic regression model that predicted that vaccine efficacy could be extended to target 46% of a population of clinically relevant strains. Immuno-manipulation of poultry microbiomes towards less harmful commensal isolates by competitive exclusion, has major potential for reducing pathogens in the food production chain.

microbiology↗