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Telfer, A.

Publications and source records attributed to Telfer, A..

2 recordsLinked to original sources

Inverse Reinforcement Learning to Study Motivation in Mouse Behavioral Paradigms

Motivation describes the underlying goals that drive animal and agent behavior. In Neuroscience, behavioral paradigms are used to quantify the motivations of mice and used to gain insights into traits and diseases which can be translated to humans. In recent years, Computer Vision models are becoming widely adopted by Neuroscientists to score mouse behavior associated with motivations such as hunger and anxiety. However, a single motivation can be expressed by multiple different behaviors, and a single behavior can be linked to multiple motivations. Therefore the ideal analysis of motivational paradigms would attempt to directly recover the underlying motivations guiding behavior, rather than indirectly score their associated behaviors. In this paper, we move towards this goal by applying Inverse Reinforcement Learning to study the underlying motivations that drive mouse behavior.

animal behavior and cognition↗

Scale-sensitive Mouse Facial Expression Pipeline using a Surrogate Calibration Task

Emotions are complex neuro-physiological states that influence behavior. While emotions have been instrumental to our survival, they are also closely associated with prevalent disorders such as depression and anxiety. The development of treatments for these disorders has relied on animal models, in particular, mice are often used in pre-clinical testing. To compare effects between treatment groups, researchers have increasingly used machine learning to help quantify behaviors associated with emotionality. Previous work has shown that computer vision can be used to detect facial expressions in mice. In this work, we create a novel dataset for depressive-like mouse facial expressions using varying LypoPolySaccharide (LPS) dosages and demonstrate that a machine learning model trained on this dataset was able to detect differences in magnitude via dosage amount.

animal behavior and cognition↗