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Biology subjects

Taylor, A. F.

Publications and source records attributed to Taylor, A. F..

3 recordsLinked to original sources

Invertebrate species produce taxon-specific acoustic profiles under controlled conditions

Soil degradation threatens food security, climate regulation, biodiversity and human wellbeing worldwide. Up to 75% of the worlds soils are already degraded, and in response, global restoration efforts are rapidly scaling up to meet international targets. Monitoring soil biodiversity recovery remains a major barrier to tracking restoration success, particularly for invertebrates that underpin key processes including nutrient cycling and soil aggregation. Traditional sampling methods are labour-intensive, destructive and poorly suited to long-term or landscape-scale monitoring. Soil ecoacoustics is rapidly emerging as a promising non-destructive soil biodiversity monitoring tool. However, its capacity for taxonomic resolution of invertebrate groups remains untested. Here, we present a proof-of-concept study that establishes the potential for a soil invertebrate acoustic classifier. We used a low-cost, sound-attenuated recording system and quantified 19 spectral and temporal audio features from six morphologically and behaviourally distinct invertebrate species under controlled conditions. Acoustic profiles differed among taxa and generally clustered into podous and apodous groups (i.e., organisms with legs versus those without). Variation was driven primarily by taxon identity rather than body mass, suggesting that acoustic signatures capture taxon-specific traits. This work provides a foundation for developing automated acoustic classifiers that could enable scalable, non-destructive soil biodiversity monitoring.

ecology↗

Intergenerational hormesis is regulated by heritable 18S rRNA methylation

Heritable non-genetic information can regulate a variety of complex phenotypes. However, what specific non-genetic cues are transmitted from parents to their descendants are poorly understood. Here, we perform metabolic methyl-labelling experiments to track the heritable transmission of methylation from ancestors to their descendants in the nematode Caenorhabditis elegans. We find that methylation is transmitted to descendants in proteins, RNA, DNA and lipids. We further find that in response to parental starvation, fed naive progeny display reduced fertility, increased heat stress resistance, and extended longevity. This intergenerational hormesis is accompanied by a heritable increase in N6-dimethyl adenosine (m6,2A) on the 18S ribosomal RNA at adenosines 1735 and 1736. We identified the conserved DIMT-1 as the m6,2A methyltransferase in C. elegans and find that dimt-1 is required for the intergenerational hormesis phenotypes. This study provides the first labeling and tracking of heritable non-genetic material across generations and demonstrates the importance of rRNA methylation for regulating the heritable response to starvation.

genetics↗

Pathway of intramolecular signal transductionfor Chi hotspot control of RecBCD helicase-nuclease

Repair of broken DNA by homologous recombination requires coordinated enzymatic reactions to prepare it for interaction with intact DNA. The multiple activities of enterobacterial RecBCD helicase-nuclease are coordinated by Chi recombination hotspots (5 GCTGGTGG 3) recognized during DNA unwinding. Chi is recognized in a tunnel in RecC but activates the RecB nuclease, >25 A' away. How the Chi-dependent signal travels this long distance has been unknown. We found a Chi-recognition-deficient mutant in the RecB helicase domain located >45 A' from both the Chi-recognition site and the nuclease active site. This unexpected observation led us to find additional mutations that reduced or eliminated Chi hotspot activity in each subunit and widely scattered throughout RecBCD. Each mutation alters the intimate contact between one or another pair of subunits in the crystal or cryoEM structures of RecBCD bound to DNA. Collectively, these mutations span a path [~]185 A' long from the Chi recognition site to the nuclease active site. We discuss these surprising results in the context of an intramolecular signal transduction accounting for many previous observations.

molecular biology↗