Search bioRxiv⌕ Search

Biology subjects

Tabi, A.

Publications and source records attributed to Tabi, A..

10 recordsLinked to original sources

A generalized metabolic theory for marine ecosystems

Marine species inhabit a three-dimensional stratified environment where metabolism is simultaneously influenced by decreasing temperature and increasing hydrostatic pressure with ocean depth. While the Metabolic Theory of Ecology (MTE) incorporates the effects of body mass and temperature, for marine organisms it neglects one of the fundamental thermodynamic state variables governing biochemical reaction kinetics: hydrostatic pressure. We derive a generalized metabolic theory by extending MTE with transition-state theory by explicitly incorporating pressure sensitivity into the Arrhenius formulation. The resulting model predicts that hydrostatic pressure increases the effective activation energy of biochemical reactions, leading to progressively lower metabolic rates with increasing depth. We tested this prediction using a global database comprising 689 metabolic measurements across 11 marine phyla and 22 taxonomic classes. Incorporating hydrostatic pressure substantially improved model performance relative to the classical MTE. Across major marine taxa, activation energy and activation volume varied largely independently, suggesting that pressure adaptation does not require corresponding changes in thermal sensitivity. Our results suggest that hydrostatic pressure is a fundamental thermodynamic constraint that regulates the pace of life across the ocean and consequently the ecological dynamics across Earths largest biome.

ecology↗

Virome-mediated ecological firewalls govern pathogen eradication in the gut microbiome

Microbiome recovery after antibiotic-induced dysbiosis is often unpredictable, and the ecological mechanisms governing successful gut microbiome restoration remain unclear. Here we introduce a novel dynamical model of bacteria-phage-pathogen interactions to examine how gut virome reshapes gut microbiome states. The model identifies pathogen eradication thresholds and shows that recovery is strongly history-dependent, with bistability allowing either clearance or persistence depending on past conditions. Viral adsorption rates strongly regulate invasion probability and recurrence susceptibility, while microbial diversity enhances stability. Furthermore, we identify an ecological "firewall" mechanism in which the resident microbiome maintains a standing virome community that suppresses pathogen invasion and stabilizes healthy microbiome. These results reveal general ecological principles governing virus-mediated microbiome recovery and inform the design of virome-based therapeutic strategies.

ecology↗

Ecological constraints to mirror life

Our biosphere exhibits remarkable diversity yet is constrained by universal organizational principles, including molecular homochirality. Advances in synthetic biology have raised the possibility of engineering alternative life forms based on mirror-image biomolecules, prompting both technological interest and biosecurity concerns. While current discussions of mirror life largely emphasize molecular feasibility and cellular function, its potential establishment in natural environments remains poorly understood. Here, we develop a theoretical framework to assess the invasion potential of mirror organisms within existing ecosystems. Using population-level models that incorporate resource competition, metabolic constraints, and ecological network interactions, we show that mirror life might face severe limitations arising from both nutrient incompatibility and competitive exclusion by established biota. In particular, the reliance on rare or achiral substrates and the asymmetry of interactions with natural organisms constrain growth and persistence across a broad range of ecological conditions. These results highlight the importance of ecological constraints in evaluating the risks and feasibility of synthetic life.

ecology↗

Information-Theoretic Origins of Metabolic Scaling

Universal scaling laws are a signature of complex biological systems, yet the mechanisms by which microscopic stochastic processes generate robust macroscopic behaviour remain debated. Here we develop an information-theoretic approach to identify robust biological scaling using a stochastic ontogenetic growth model, in which correlated cellular bursts propagate from microscopic noise to organism-level metabolic fluctuations. We show that an information-neutral regime, defined as the minimum Kullback-Leibler divergence between fluctuation distributions generated under different microscopic correlation structures, identifies stochastic regimes for which macroscopic observables become maximally insensitive to microscopic details. Within this regime, metabolic scaling exponents converge across species sizes to a narrow range close to linear scaling relationship. The information-theoretic optimum is robust to temporal coarse-graining, indicating non-critical scale robustness without requiring proximity to a phase transition. Our results suggest that information neutrality provides a general principle for identifying robust stochastic mechanisms underlying biological scaling and illustrate how universal macroscopic behaviour can emerge from noisy microscopic dynamics.

ecology↗

Metabolic fluctuations explain allometric scaling diversity

Metabolic scaling, the relationship between energy use and body size, has long been treated as a universal law of life. However, extensive variation in scaling exponents across species challenges this assumption. Here, we show that such scaling can emerge spontaneously from stochastic cellular growth dynamics, without postulating any fixed relationship between mass and metabolism. In our framework, ontogeny is a nonequilibrium thermodynamic process in which energy is continuously dissipated and redistributed among fluctuating cellular states. When applied across diverse life histories, the model reproduces the observed range of metabolic exponents, revealing that scaling diversity arises naturally from fundamental thermodynamic constraints on stochastic, energy-dissipating growth.

ecology↗

The ecological memory of landscape complexity shapes diversity of freshwater communities

Land use change affects the biodiversity of terrestrial landscapes as well as of the freshwater systems they surround, and thereby numerous ecosystem services that are essential for human well-being. Previous research suggests that freshwater systems show delayed responses to abrupt disturbances such as deforestation, however less is known about whether there is a legacy effect of landscape history on freshwater communities under a long history of land use change. We addressed this research gap here by first quantifying the historical complexity of landscapes, including natural and agricultural formations, in terms of their composition and configuration in 26 tropical catchment areas surrounding 101 streams over a 30-year period. We identified clear evidence for a memory effect of past events, whereby historical landscape complexity, measured as the information entropy of landscape composition, positively affected freshwater biodiversity. Finally, using a causal discovery approach, we showed that species richness was causally related to landscape complexity only when historical values were incorporated. Our results corroborate previous work on the positive effect of landscape complexity on biodiversity, and also confirm the role of historical contingencies in predicting future ecological outcomes.

ecology↗

Species interactions drive continuous assembly of freshwater communities in stochastic environments

Understanding the factors driving the maintenance of long-term biodiversity in changing environments is essential for improving restoration and sustainability strategies in the face of global environmental change. Biodiversity is shaped by both niche and stochastic processes, however the strength of deterministic processes in unpredictable environmental regimes is highly debated. Since communities continuously change over time and space -- species persist, disappear or (re)appear -- understanding the drivers of species gains and losses from communities should inform us about whether niche or stochastic processes dominate community dynamics. Applying a nonparametric causal discovery approach to a 30-year time series containing annual abundances of benthic invertebrates across 66 locations in New Zealand rivers, we found a strong asynchronous causal relationship between species gains and losses directly driven by predation indicating that niche processes dominate community dynamics. Despite the unpredictable nature of these system, environmental noise was only indirectly related to species gains and losses through altering life history trait distribution. Using a stochastic birth-death framework, we demonstrate that the negative relationship between species gains and losses can not emerge without strong niche processes. Our results showed that even in systems that are dominated by unpredictable environmental variability, species interactions drive continuous community assembly.

ecology↗

Marine protected areas regulate the structure of fish communities threatened by global warming and human impact

The sustainability of marine communities is critical for supporting many biophysical processes that provide ecosystem services that promote human well-being. It is expected that anthropogenic disturbances such as climate change and human activities will tend to create less energetically-efficient ecosystems that support less biomass per unit energy flow. It is debated, however, whether this expected development should translate into bottom-heavy (with small basal species being the most abundant) or top-heavy communities (where more biomass is supported at higher trophic levels with species having larger body sizes). Here, we combine ecological theory and empirical data to demonstrate that full marine protection promotes shifts towards top-heavy energetically-efficient structures in marine communities. First, we use metabolic scaling theory to show that protected communities are expected to display stronger top-heavy structures than disturbed communities. Similarly, we show theoretically that communities with high energy transfer efficiency display stronger top-heavy structures than communities with low transfer efficiency. Next, we use empirical structures observed within fully protected marine areas compared to disturbed areas that vary in stress from thermal events and adjacent human activity. Using a nonparametric causal-inference analysis, we find a strong, positive, causal effect between full marine protection and stronger top-heavy structures. Our work corroborates ecological theory on community development and provides a quantitative framework to study the potential restorative effects of different candidate strategies on protected areas. PO_SCPLOWREPRINTC_SCPLOWThe manuscript [1] is deposited on bioRxiv (https://doi.org/10.1101/2022.06.02.494503).

ecology↗

An integrative study to understand the temperature-size rule with nonlinear temperature increase: One approach to rule them all?

The temperature-size rule (TSR) describes the inverse relationship between organism size and environmental temperature in uni- and multicellular species. Despite the TSR being widespread, the mechanisms for shrinking body size with warming remain elusive. Here, we experimentally test three hypotheses (differential development and growth [DDG], maintain aerobic scope and regulate oxygen supply [MASROS] and the supply-demand hypothesis [SD]) potentially explaining the TSR using the aquatic protist Colpidium striatum in three gradually changing and one constant temperature environment crossed with three different nutrient levels. We find that the constant and slowly warming environments show similar responses in terms of population dynamics, whereas populations with linear and fast warming quickly decline and show a stronger temperature-size response. Our analyses suggest that acclimation may have played a role in observing these differences among treatments. The SD hypothesis is most parsimonious with the data, however, neither the DDG nor the MASROS hypothesis can be firmly dismissed. We conclude that the TSR is driven by multiple ecological and acclimatory responses and hence multicausal. Author statementA.T. designed and led the experiment, and A.T. and A.G. performed the sampling. A.T. and F.P. analyzed and interpreted the data. All authors contributed to the writing of the manuscript.

ecology↗

The intrinsic predictability of ecological time series and its potential to guide forecasting

Successfully predicting the future states of systems that are complex, stochastic and potentially chaotic is a major challenge. Model forecasting error (FE) is the usual measure of success; however model predictions provide no insights into the potential for improvement. In short, the realized predictability of a specific model is uninformative about whether the system is inherently predictable or whether the chosen model is a poor match for the system and our observations thereof. Ideally, model proficiency would be judged with respect to the systems intrinsic predictability - the highest achievable predictability given the degree to which system dynamics are the result of deterministic v. stochastic processes. Intrinsic predictability may be quantified with permutation entropy (PE), a model-free, information-theoretic measure of the complexity of a time series. By means of simulations we show that a correlation exists between estimated PE and FE and show how stochasticity, process error, and chaotic dynamics affect the relationship. This relationship is verified for a dataset of 461 empirical ecological time series. We show how deviations from the expected PE-FE relationship are related to covariates of data quality and the nonlinearity of ecological dynamics.\n\nThese results demonstrate a theoretically-grounded basis for a model-free evaluation of a systems intrinsic predictability. Identifying the gap between the intrinsic and realized predictability of time series will enable researchers to understand whether forecasting proficiency is limited by the quality and quantity of their data or the ability of the chosen forecasting model to explain the data. Intrinsic predictability also provides a model-free baseline of forecasting proficiency against which modeling efforts can be evaluated.\n\nGlossaryActive information: The amount of information that is available to forecasting models (redundant information minus lost information; Fig. 1).\n\nO_FIG O_LINKSMALLFIG WIDTH=200 HEIGHT=45 SRC=\"FIGDIR/small/350017_fig1a.gif\" ALT=\"Figure 1A\">\nView larger version (9K):\norg.highwire.dtl.DTLVardef@934d9eorg.highwire.dtl.DTLVardef@ccdc10org.highwire.dtl.DTLVardef@1839ed9org.highwire.dtl.DTLVardef@31bd70_HPS_FORMAT_FIGEXP M_FIG O_FLOATNOFigure 1A.C_FLOATNO The total information content of an observation of a system at a given state in time, St, is depicted by filled circles with past states (St-1 and St-2) represented by shades of grey, i) lack of overlap between past and present states illustrating a case where no information is transmitted from past states (i.e. a purely stochastic system), with low redundancy and high Shannon entropy rate, ii) intermediate overlap indicating a case when some information is transferred from past to present (i.e. a deterministic system strongly driven by stochastic forcing), with intermediate redundancy and Shannon entropy rate, iii) large overlap indicating a case when the current state is mostly determined by the previous state (i.e. a highly deterministic system), with high redundancy and low Shannon entropy rate. Note that both the redundancy and Shannon entropy rate of a system are intrinsic properties of the system and will only change if the system itself changes.\n\nC_FIG Forecasting error (FE): A measure of the discrepancy between a models forecasts and the observed dynamics of a system. Common measures of forecast error are root mean squared error and mean absolute error.\n\nEntropy: Measures the average amount of information in the outcome of a stochastic process.\n\nInformation: Any entity that provides answers and resolves uncertainty about a process. When information is calculated using logarithms to the base two (i.e. information in bits), it is the minimum number of yes/no questions required, on average, to determine the identity of the symbol (Jost 2006). The information in an observation consists of information inherited from the past (redundant information), and of new information.\n\nIntrinsic predictability: the maximum achievable predictability of a system (Beckage et al. 2011).\n\nLost information: The part of the redundant information lost due to measurement or sampling error, or transformations of the data (Fig. 1).\n\nNew information, Shannon entropy rate: The Shannon entropy rate quantifies the average amount of information per observation in a time series that is unrelated to the past, i.e., the new information (Fig. 1).\n\nNonlinearity: When the deterministic processes governing system dynamics depend on the state of the system.\n\nPermutation entropy (PE): permutation entropy is a measure of the complexity of a time series (Bandt & Pompe, 2002) that is negatively correlated with a systems predictability (Garland et al. 2015). Permutation entropy quantifies the combined new and lost information. PE is scaled to range between a minimum of 0 and a maximum of 1.\n\nRealized predictability: the achieved predictability of a system from a given forecasting model.\n\nRedundant information: The information inherited from the past, and thus the maximum amount of information available for use in forecasting (Fig. 1).\n\nSymbols, words, permutations: symbols are simply the smallest unit in a formal language such as the letters in the English alphabet i.e., {\"A\", \"B\",..., \"Z\"}. In information theory the alphabet is more abstract, such as elements in the set {\"up\", \"down\"} or {\"1\", \"2\", \"3\"}. Words, of length m refer to concatenations of the symbols (e.g., up-down-down) in a set. Permutations are the possible orderings of symbols in a set. In this manuscript, the words are the permutations that arise from the numerical ordering of m data points in a time series.\n\nWeighted permutation entropy (WPE): a modification of permutation entropy (Fadlallah et al., 2013) that distinguishes between small-scale, noise-driven variation and large-scale, system-driven variation by considering the magnitudes of changes in addition to the rank-order patterns of PE.

ecology↗