Biology subjects

Shinkareva, S. V.

Publications and source records attributed to Shinkareva, S. V..

3 recordsLinked to original sources

bioRxiv2024

Embracing naturalistic paradigms: substituting GPT predictions for human judgments

Naturalistic paradigms can assure ecological validity and yield novel insights in psychology and neuroscience. However, using behavioral experiments to obtain the human ratings necessary to analyze data collected with these paradigms is usually costly and time-consuming. Large language models like GPT have great potential for predicting human-like behavioral judgments. The current study evaluates the performance of GPT as a substitute for human judgments for affective dynamics in narratives. Our results revealed that GPTs inference of hedonic valence dynamics is highly correlated with human affective perception. Moreover, the inferred neural activity based on GPT-derived valence ratings is similar to inferred neural activity based on human judgments, suggesting the potential of using GPTs prediction as a reliable substitute for human judgments.

neuroscience↗

bioRxiv2024

Physiological Processing of Aversiveness in the Mind's Ear: Comparing Audiovisual, Auditory and Imagined Auditory Affective Stimuli

Understanding the somatovisceral responses to auditory affective imagery has important implications in disorders like misophonia. The current study compared physiological responses to aversive and nonaversive states across three modalities: audiovisual, auditory, and auditory imagery. Electromyographic activity over corrugator supercilii (EMGc) and zygomaticus major (EMGz), electrodermal activity (EDA), heart rate (HR), and finger skin temperature (SKT) were measured. There was significant differentiation in EMGc, EDA, and HR deceleration between aversive and nonaversive audiovisual stimuli. EMGc potentiation was the only physiological measure showing consistent differentiation across the three modalities. Cross-modal aversiveness classification results revealed a similar physiological response pattern between audiovisual and auditory modalities. The physiological response pattern during auditory affective imagery was useful for predicting the aversiveness in audiovisual modality but not the other way around. Vividness in auditory imagery correlated with subjective hedonic valence ratings, but not physiological responses. Taken together, the current data suggest that the aversiveness of auditory imagery is differentiable in subjective affective experience and facial muscle potentiation. These results of the physiological responses to imagined aversive sounds in nonclinical population would serve as a comparison baseline for the study of misophonia.

physiology↗

bioRxiv2022

Audiovisual Integration in the Human Brain: A Coordinate-based Meta-analysis

People can seamlessly integrate a vast array of information from what we see and hear in the noisy and uncertain world. However, the neural underpinnings of audiovisual integration continue to be the topic of debate. Using strict inclusion criteria, we performed activation likelihood estimation meta-analysis on 121 neuroimaging experiments with a total of 2,092 participants. We found that audiovisual integration is linked with the coexistence of multiple integration sites including early cortical, subcortical, and higher association areas. Although activity was consistently found within the superior temporal cortex, different portions of this cortical region were identified depending on the analytical contrast used, complexity of the stimuli, and modality within which attention was directed. The context-dependent neural activity related to audiovisual integration suggests a flexible rather than fixed neural pathway for audiovisual integration. Together, our findings highlight a flexible multiple pathways model for audiovisual integration, with superior temporal cortex as the central node in these neural assemblies.

neuroscience↗