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Senk, J.

Publications and source records attributed to Senk, J..

2 recordsLinked to original sources

A mean-field toolbox for spiking neuronal network model analysis

Mean-field theory of spiking neuronal networks has led to numerous advances in our analytical and intuitive understanding of the dynamics of neuronal network models during the past decades. But, the elaborate nature of many of the developed methods, as well as the difficulty of implementing them, may limit the wider neuroscientific community from taking maximal advantage of these tools. In order to make them more accessible, we implemented an extensible, easy-to-use open-source Python toolbox that collects a variety of mean-field methods for the widely used leaky integrate-and-fire neuron model. The Neuronal Network Mean-field Toolbox (NNMT) in its current state allows for estimating properties of large neuronal networks, such as firing rates, power spectra, and dynamical stability in mean-field and linear response approximation, without running simulations on high performance systems. In this article we describe how the toolbox is implemented, show how it is used to calculate neuronal network properties, and discuss different use-cases, such as extraction of network mechanisms, parameter space exploration, or hybrid modeling approaches. Although the initial version of the toolbox focuses on methods that are close to our own past and present research, its structure is designed to be open and extensible. It aims to provide a platform for collecting analytical methods for neuronal network model analysis and we discuss how interested scientists can share their own methods via this platform.

neuroscience↗

NEST Desktop - An educational application for neuroscience

Simulation software for spiking neuronal network models matured in the past decades regarding performance and flexibility. But the entry barrier remains high for students and early career scientists in computational neuroscience since these simulators typically require programming skills and a complex installation. Here, we describe an installation-free Graphical User Interface (GUI) running in the web browser, which is distinct from the simulation engine running anywhere, on the students laptop or on a supercomputer. This architecture provides robustness against technological changes in the software stack and simplifies deployment for self-education and for teachers. Our new open source tool, NEST Desktop, comprises graphical elements for creating and configuring network models, running simulations, and visualizing and analyzing the results. NEST Desktop allows students to explore important concepts in computational neuroscience without the need to learn a simulator control language before. Our experiences so far highlight that NEST Desktop helps advancing both quality and intensity of teaching in computational neuroscience in regular university courses. We view the availability of the tool on public resources like the European ICT infrastructure for neuroscience EBRAINS as a contribution to equal opportunities. Significance StatementThe graphical user interface NEST Desktop makes neuronal network simulations accessible to non-programmers. It facilitates the interactive exploration of neuronal network models by integrating the whole workflow of wiring up the setup, simulating the neuronal dynamics, and analyzing the recorded activity data into a single tool. NEST Desktop effectively supports teaching the concepts and methods of computational neuroscience. Due to its installation-free web-based implementation, it is in particularly suitable for online courses.

neuroscience↗