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Pelivanov, I.

Publications and source records attributed to Pelivanov, I..

2 recordsLinked to original sources

DINOCT: robust skin surface localization for robotic noncontact dynamic optical coherence elastography

Noncontact dynamic optical coherence elastography (OCE) can measure the elastic properties of anterior soft tissues. However, applying OCE to skin requires tracking mechanical waves propagating in multiple directions to reconstruct mechanical anisotropy. Robotic scanning is well suited to this task but requires accurate probe positioning, alignment to the surface normal, and precise, repeatable rotation. To ensure phase and polarization stability, polarization-maintaining (PM) fibers can be used, although they introduce stripe and ghost artifacts that can destabilize surface detection. We present DINOCT, a DINO-based method to localize the skin surface from optical coherence tomography (OCT) images that combines self-supervised pretraining with DINO (self-DIstillation with NO labels) and iBOT (image BERT pre-training with Online Tokenizer) objectives, low-rank adaptation, and a lightweight curve decoder. Compared with classical and supervised learning baselines, DINOCT achieved competitive localization accuracy on clean test data with a near-zero spike rate. Among the learned methods, DINOCT achieved the lowest average and maximum values of mean absolute error (MAE) for severe synthetic stress conditions and the lowest catastrophic failure rates on a separate recording with strong PM-fiber artifacts.

bioengineering↗

Real-time spectroscopic photoacoustic/ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction for quantitative molecular imaging

For over two decades photoacoustic (PA) imaging has been tested clinically, but successful human trials have been minimal. To enable quantitative clinical spectroscopy, the fundamental issues of wavelength-dependent fluence variations and inter-wavelength motion must be overcome. Here we propose a new real-time, spectroscopic photoacoustic/ultrasound (PAUS) imaging approach using a compact, 1-kHz rate wavelength-tunable laser. Instead of illuminating tissue over a large area, the fiber-optic delivery system surrounding an US array sequentially scans a narrow laser beam, with partial PA image reconstruction for each laser pulse. The final image is then formed by coherently summing partial images at a 50-Hz video rate. This scheme enables (i) automatic laser-fluence compensation in spectroscopic PA imaging and (ii) inter-wavelength motion correction using US speckle tracking, which have never been shown before in real-time systems. The 50-Hz video rate PAUS system is demonstrated in vivo using a murine model of drug delivery monitoring.

bioengineering↗