Pardi, B. M. | Search bioRxiv

bioRxiv2023

pyQCM-BraTaDio: A tool for visualization, data mining, and modeling of Quartz crystal microbalance with dissipation data

Here, we present a Python based software that allows for the rapid visualization, data mining, and basic model applications of quartz crystal microbalance with dissipation data. Our implementation begins with a Tkinter GUI to prompt the user for all required information, such as file name/location, selection of baseline time, and overtones for visualization (with customization capabilities). These inputs are then fed to a workflow that will use the baseline time to scrub and temporally shift data using the Pandas and Numpy libraries and carry out the plot options for visualization. The last stage consists of an interactive plot, that presents the data and allows the user to select ranges in MatPlotLib-generated panels, followed by application of data models, including Sauerbrey, thin films in liquid, among others, that are carried out with NumPy and SciPy. The implementation of this software allows for simple and expedited data analysis, in lieu of time consuming and labor-intensive spreadsheet analysis. Metadata O_TBL View this table: org.highwire.dtl.DTLVardef@1da584dorg.highwire.dtl.DTLVardef@1db3baborg.highwire.dtl.DTLVardef@2a90ecorg.highwire.dtl.DTLVardef@90877aorg.highwire.dtl.DTLVardef@ae672f_HPS_FORMAT_FIGEXP M_TBL C_TBL

bioengineering↗

bioRxiv2023

Facile determination of the Poisson's ratio and Young's modulus of polyacrylamide gels and polydimethylsiloxane

Polyacrylamide hydrogels (PAH) and polydimethylsiloxane (PDMS) are two soft materials often used in cell mechanics and mechanobiology, in manufacturing lab-on-a chip applications, among others. This is partly due to the ability to tune their elasticity with ease, in addition to various chemical modifications. For affine polymeric networks, two (of three) elastic constants - the Youngs modulus (E), the shear modulus (G), and the Poissons ratio ({nu}) - describe the purely elastic response to external forces. However, the literature addressing the experimental determination of {nu} for PAH (also sometimes referred to as PAA gels in the literature) and PDMS is surprisingly limited when compared to the literature reporting values of E and G. Here, we present a facile method to obtain the Poisons ratio and Youngs modulus for PAH and PDMS based on static tensile tests, and cross-correlate these values with those obtained via a second independent method, shear rheology. We show that: i) the Poissons ratio may vary significantly from the value for incompressible materials ({nu} = 0.5), and ii) find a high degree of agreement between shear rheology and macroscopic static tension tests for PAH but not PDMS. O_FIG O_LINKSMALLFIG WIDTH=200 HEIGHT=121 SRC="FIGDIR/small/540222v1_ufig1.gif" ALT="Figure 1"> View larger version (24K): org.highwire.dtl.DTLVardef@120116forg.highwire.dtl.DTLVardef@58acbcorg.highwire.dtl.DTLVardef@1b48683org.highwire.dtl.DTLVardef@eb3fda_HPS_FORMAT_FIGEXP M_FIG C_FIG

bioengineering↗