Biology subjects

Müller-Pinzler, L.

Publications and source records attributed to Müller-Pinzler, L..

7 recordsLinked to original sources

bioRxiv2026

Self-enhancement and devaluation of others during belief formation are linked to narcissistic traits

Background: Narcissistic personality traits are associated with the tendency to maintain a grandiose self-image through self-enhancement and devaluation of others. Using computational modeling, we investigated how narcissistic traits and the experience of pride are linked to how individuals form beliefs about themselves and others. Methods: Healthy individuals and individuals with psychiatric diagnoses varying in narcissistic traits (N = 97) completed a learning task in which self-serving biases emerged implicitly through trial-by-trial belief updating in response to manipulated feedback. Computational modeling quantified how participants updated beliefs about their own and another person's abilities in response to better- and worse-than-expected performance feedback. Results: Higher narcissistic traits were associated with reduced learning from worse-than-expected self-related feedback, consistent with self-enhancement as a mechanism for maintaining a grandiose self-image. Individuals with higher narcissistic traits also reported greater pride following better-than-expected self-related feedback, which mediated the association between narcissistic traits and positive self-related learning. Furthermore, higher narcissistic traits were, mediated via pride, linked to increased learning from worse-than-expected feedback about the other person, suggesting that devaluing others relative to oneself may serve as a secondary pathway for maintaining a grandiose self-image. Discussion: These findings identify computational and affective mechanisms through which narcissistic traits are linked to self- and other-related belief formation. Reduced integration of negative self-related feedback together with enhanced pride following positive feedback may support grandiose self-beliefs, while enhanced learning from negative information about others suggests that individuals with higher narcissistic traits implicitly construct themselves as superior through both self-enhancement and devaluation of others during interpersonal belief formation.

neuroscience↗

bioRxiv2024

Time-of-day related fluctuations of self-belief formation

Time of day influences a variety of human cognitive processes, including attention, executive functions and memory formation, as well as affective experiences and mood. However, circadian modulations of self-related learning and belief formation, which are highly affected by emotional states, remain poorly understood. Here, we present results from exploratory post-hoc analyses on data aggregated from five studies assessing the formation of self-related ability beliefs. A total of N=242 healthy participants completed a validated learning task at different times of the day, during which they continuously received feedback on their performance. Computational modeling was applied to quantify participants learning behavior during the task. Results suggest an association between time-of-day and self-belief formation, showing that participants who were tested in the evening (7:00-9:59 p.m.) updated their self-beliefs more strongly in response to the received feedback compared to those tested in the afternoon (1:00-3:59 p.m.). Evidence from additional models indicated that these differences were driven by non-linear, rhythmic changes in self-belief formation across different times of the day. Future studies should systematically examine within-subject fluctuations in self-belief formation across the day and address the influence of individual factors such as chronotype, age, mood and sleep quality. Understanding circadian modulations of self-related belief formation could contribute to optimized interventions for conditions characterized by maladaptive self-beliefs, such as depression, as well as in academic contexts.

neuroscience↗

bioRxiv2024

Neurocomputational Mechanisms Underlying Maladaptive Self-Belief Formation in Depression

Maladaptive self-beliefs are a core symptom of major depressive disorder. These beliefs are perpetuated by a negatively biased integration of self-related feedback. Understanding the neurocomputational mechanisms of biased belief updating may help to counteract maladaptive beliefs and the maintenance of depression. The present study uses a belief-updating task and functional neuroimaging to examine the neurocomputational mechanisms associated with self-related feedback processing in individuals with major depression and matched healthy controls. We hypothesized that increased symptom burden in depression is associated with negatively biased self-belief updating and altered neural tracking of social feedback. Our findings show that depression is related to reduced incorporation of unexpected positive feedback, with higher symptom burden alongside heightened insula reactivity to unexpected negative feedback. The interplay of increased neural responsiveness to negative feedback and the reduced learning from positive feedback provide new insights into cognitive distortions in depression and may explain the persistence of maladaptive self-beliefs and, thus, the maintenance of depression.

neuroscience↗

bioRxiv2021

Computational and neural mechanisms of affected beliefs

The feedback people receive on their behavior shapes the process of belief formation and self-efficacy in mastering a given task. However, the neural and computational mechanisms of how the subjective value of these beliefs, and the corresponding affect, bias the learning process remain unclear. We investigated these mechanisms during the learning of self-efficacy beliefs using fMRI, pupillometry, and computational modeling, and by analyzing individual differences in affective experience. Biases in the formation of self-efficacy beliefs were associated with affect, pupil dilation, and neural activity within the anterior insula, amygdala, ventral tegmental area/ substantia nigra, and mPFC. Specifically, neural and pupil responses map the valence of the prediction errors in correspondence with individuals experienced affect and learning bias during belief formation. Together with the functional connectivity dynamics of the anterior insula within this network, our results hint at neural and computational mechanisms that integrate affect into the process of belief formation.

neuroscience↗

bioRxiv2021

Intracortical human recordings reveal intensity coding for the pain of others in the insula

Based on neuroimaging data, the insula is considered important for people to empathize with the pain of others, whether that pain is perceived through facial expressions or the sight of limbs in painful situations. Here we present the first report of intracranial electroencephalographic (iEEG) recordings from the insulae collected while 7 presurgical epilepsy patients rated the intensity of a womans painful experiences viewed in movies. In two separate conditions, pain was deduced from seeing facial expressions or a hand being slapped by a belt. We found that broadband activity in the 20-190 Hz range correlated with the trial-by-trial perceived intensity in the insula for both types of stimuli. Using microwires at the tip of a selection of the electrodes, we additionally isolated 8 insular neurons with spiking that correlated with perceived intensity. Within the insula, we found a patchwork of locations with differing selectivities within our stimulus set, some representing intensity only for facial expressions, others only for the hand being hit, and others for both. That we found some locations with intensity coding only for faces, and others only for hand across simultaneously recorded locations suggests that insular activity while witnessing the pain of others cannot be entirely reduced to a univariate salience representation. Psychophysics and the temporal properties of our signals indicate that the timing of responses encoding intensity for the sight of the hand being hit are best explained by kinematic information; the timing of those encoding intensity for facial expressions are best explained by shape information in the face. In particular, the furrowing of the eyebrows and the narrowing of the eyes of the protagonist in the movies suffice to predict both the rating of and the timing of the neuronal response to the facial expressions. Comparing the broadband activity in the iEEG signal with spiking activity and an fMRI experiment with similar stimuli revealed a consistent spatial organization for the representation of intensity from our hand stimuli, with stronger intensity representation more anteriorly and around neurons with intensity coding. In contrast, for the facial expressions, we found that the activity at the three levels of measurement do not coincide, suggesting a more disorganized representation. Together, our intracranial recordings indicate that the insula encodes, in a partially intermixed layout, both static and dynamic cues from different body parts that reflect the intensity of pain experienced by others.

neuroscience↗

bioRxiv2020

Self-beneficial belief updating as a coping mechanism for stress-induced negative affect

Being confronted with social-evaluative stress elicits a physiological and a psychological stress response. This calls for regulatory processes to manage negative affect and maintain self-related optimistic beliefs. The aim of the current study was to investigate the affect-regulating potential of self-related belief updating after exposure to social-evaluative stress, in comparison to non-social physical stress or no stress. We assessed self-related belief updating using trial-by-trial performance feedback and described the updating behavior in a mechanistic way using computational modeling. We found that social-evaluative stress was accompanied by an increase in cortisol and negative affect which was related to a shift in self-related belief updating towards the positive direction. This self-beneficial belief updating, which was absent after physical stress or control, was associated with a better recovery from stress-induced negative affect. This indicates that enhanced integration of positive self-related feedback can act as a coping strategy to deal with social-evaluative stress.

neuroscience↗

bioRxiv2019

Subjectively perceived control drives affective, neural, and motivational markers of self-related outcome valuation

Experiencing events as controllable and attributing positive outcomes to own contributions is essential for human well-being. Based on classic psychological theory we test how internal control beliefs impact the affective valuation of task outcomes, neural dynamics and ensuing behavioral preferences. In three consecutive studies with independent samples we show that dynamics in self-evaluative affect specifically increase when agents believe they caused a given task outcome. We demonstrate that these outcomes engage brain networks processing self-referential information in the cortical midline. Here, activity in the ventromedial prefrontal cortex tracks outcome valence regarding both success as well as internal control, and covaries with self-evaluative affect. These affective dynamics also relate to increased functional coupling between the ventral striatum and cortical midline structures. Finally, we show that self-evaluative affect promotes preferences for control, even at a monetary cost. Our investigations extend recent models of positive affect and well-being, and emphasize that control beliefs drive intrinsic motivation.

neuroscience↗