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Biology subjects

Kungurtsev, V.

Publications and source records attributed to Kungurtsev, V..

2 recordsLinked to original sources

Effect of Weather and Soil on Medicinal Plant Production in East African Arid Acacias: A Simulation Study

1In African countries various tree spcies are a key part in Non Timber Forest Production (NTFP) economy, be it for fruit, resin collection or medicinal use. Among these species Acacias play an important role in the arid and semi-arid dry-lands over Africa. In this study we explore the potential of BioGeoChemical Modelling techniques to assess growth peformance of Acacia ocurrences within their natural environment, where they only may persist against rain-fed grassland vegetation when having access to seasonally changing groundwater tables. Within this study we assess the applicability of BGC-modeling techonologies to pastoral and AgroForestry settings within a semi-arid region in Kenya. Results show that effects of (i) changing hydrological patterns, (ii) fire and grazing regimes and (iii) plant use for resin production may be captured.

ecology↗

Antiproliferative Activity, Phytochemistry, Network Pharmacology, Molecular Docking and Gene Expression Analysis of Maerua edulis Extracts against Human Cervical Cancer Cell Line

Maerua edulis exhibits significant antiproliferative activity against HeLa cells, with hexane and ethyl acetate extracts showing IC50 values of 0.02% and 47.42 {micro}g/mL, respectively. Gas Chromatography-Mass Spectrometry (GC-MS) analysis identified key phytochemicals such as diisooctyl phthalate, squalene, and stigmasta-3,5-diene, which were associated with the regulation of apoptotic and cell cycle-related genes (BCL2, CDK2, TP53). Gene expression assays confirmed the modulation of these targets, suggesting the therapeutic potential of M. edulis in cervical cancer. Further in vivo studies are recommended to validate these findings and establish its safety profile.

cancer biology↗