Gonzalez-Mora, J. L. | Search bioRxiv

bioRxiv2021

Differences in Regional Grey Matter Volume Predict the Extent to which Openness influences Judgments of Beauty and Pleasantness of Interior Architectural Spaces

Hedonic evaluation of sensory objects varies from person to person. While this variability has been linked to differences in experience and personality traits, little is known about why stimuli lead to different evaluations in different people. We used linear mixed effect models to determine the extent to which the openness, contour, and ceiling height of interior architectural spaces influenced the beauty and pleasantness ratings of 18 participants. Then, by analyzing structural brain images acquired for the same group of participants we asked if any regional grey matter volume (rGMV) co-varied with these differences in the extent to which openness, contour and ceiling height influence beauty and pleasantness ratings. Voxel-based morphometry analysis revealed that the influence of openness on pleasantness ratings correlated with rGMV in the anterior prefrontal cortex (BA 10), and the influence of openness on beauty ratings correlated with rGMV in the temporal pole (BA 38) and posterior cingulate cortex (BA 31). There were no significant correlations involving contour or ceiling height. Our results suggest that regional variance in grey matter volume may play a role in the computation of hedonic valuation, and account for differences in the way people weigh certain attributes of interior architectural spaces.

neuroscience↗

bioRxiv2020

Increases in whole brain grey matter associated with long-term Sahaja Yoga Meditation: a detailed area by area description

ObjectivesOur previous study showed that long-term practitioners of Sahaja Yoga Meditation (SYM) had around 7% larger grey matter volume (GMV) in the whole brain compared with healthy controls; however, when testing individual regions, only 5 small brain areas were statistically different between groups. Under the hypothesis that those results were statistically conservative, with the same dataset, we investigated in more detail the regional differences in GMV associated with the practice of SYM, with a different statistical approach. DesignTwenty-three experienced practitioners of SYM and 23 healthy non-meditators matched on age, gender and education level, were scanned using structural Magnetic Resonance Imaging. Their GMV were extracted and compared using Voxel-Based Morphometry. Using a novel ad-hoc GLM model, statistical comparisons were made to observe if the GMV differences between meditators and controls were statistically significant. ResultsIn the 16 lobe area subdivisions, GMV was statistically significantly different in 4 out of 16 areas: Right hemispheric temporal and frontal lobes, left frontal lobe and brainstem. In the 116 AAL area subdivisions, GMV difference was statistically significant in 11 areas. The GMV differences were statistically more significant in right hemispheric brain areas. ConclusionsThe study shows that long-term practice of SYM is associated with larger GMV overall, and with significant differences mainly in temporal and frontal areas of the right hemisphere and the brainstem. These neuroplastic changes may reflect emotional and attentional control mechanisms developed with SYM. On the other hand, our statistical ad-hoc method shows that there were more brain areas with statistical significance compared to the traditional methodology which we think is susceptible to conservative Type II errors.

neuroscience↗