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Gathercole, S. E.

Publications and source records attributed to Gathercole, S. E..

3 recordsLinked to original sources

Are working memory training effects paradigm-specific?

A randomized controlled trial compared complex span and n-back training regimes to investigate the generality of training benefits across materials and paradigms. The memory items and training intensities were equated across programs, providing the first like-with-like comparison of transfer in these two widely-used training paradigms. The stimuli in transfer tests of verbal and visuo-spatial n-back and complex span differed from the trained tasks, but were matched across the untrained paradigms. Pre-to-post changes were observed for untrained n-back tasks following n-back training. Following complex span training there was equivocal evidence for improvements on a verbal complex span task, but no evidence for changes on an untrained visuo-spatial complex span activity. Relative to a no intervention group, the evidence supported no change on an untrained verbal complex span task following either n-back or complex span training. Equivocal evidence was found for improvements on visuo-spatial complex span and verbal and visuo-spatial n-back tasks following both training regimes. Evidence for selective transfer (comparing the two active training groups) was only found for an untrained visuo-spatial n-back task following n-back training. There was no evidence for cross-paradigm transfer. Thus transfer is constrained by working memory paradigm and the nature of individual processes executed within complex span tasks. However, within-paradigm transfer can occur when the change is limited to stimulus category, at least for n-back.

neuroscience

A transdiagnostic study of children with problems of attention, learning and memory (CALM)

BackgroundA substantial proportion of the school-age population experience cognitive-related learning difficulties. Not all children who struggle at school receive a diagnosis, yet their problems are sufficient to warrant additional support. Understanding the causes of learning difficulties is the key to developing effective prevention and intervention strategies for struggling learners. The aim of this project is to apply a transdiagnostic approach to children with cognitive developmental difficulties related to learning to discover the underpinning mechanisms of learning problems.\n\nMethods / DesignA cohort of 1000 children aged 5 to 18 years is being recruited. The sample consists of 800 children with problems in attention, learning and / memory, as identified by a health or educational professional, and 200 typically-developing children recruited from the same schools as those with difficulties. All children are completing assessments of cognition, including tests of phonological processing, short-term and working memory, attention, executive function and processing speed. Their parents/ carers are completing questionnaires about the childs family history, communication skills, mental health and behaviour. Children are invited for an optional MRI brain scan and are asked to provide an optional DNA sample (saliva).\n\nHypothesis-free data-driven methods will be used to identify the cognitive, behavioural and neural dimensions of learning difficulties. Machine-learning approaches will be used to map the multi-dimensional space of the cognitive, neural and behavioural measures to identify clusters of children with shared profiles. Finally, group comparisons will be used to test theories of development and disorder.\n\nDiscussionOur multi-systems approach to identifying the causes of learning difficulties in a heterogeneous sample of struggling learners provides a novel way to enhance our understanding of the common and complex needs of the majority of children who struggle at school. Our broad recruitment criteria targeting all children with cognitive learning problems, irrespective of diagnoses and comorbidities, are novel and make our sample unique. Our dataset will also provide a valuable resource of genetic, imaging and cognitive developmental data for the scientific community.

neuroscience

Cognition and behaviour in learning difficulties and ADHD: A dimensional approach

BackgroundAcademic underachievement often accompanies the symptoms of inattention and hyperactivity/ impulsivity associated with ADHD. The aim of the present study is to establish whether learning difficulties have the same cognitive origins in this comorbid condition as in children who do not have ADHD.\n\nMethodsParticipants were 163 school-aged children with learning difficulties. Over a third also had a diagnosis of ADHD. Cognition, behaviour and learning attainments were assessed.\n\nResultsThe sample was distinguished by three cognitive and three behavioural dimensions. Learning was equivalently related to cognitive dimensions for children with and without ADHD. A diagnosis of ADHD was associated only with elevated levels of ADHD symptoms and problems with emotional control.\n\nConclusionsDistinct dimensions underpin academic learning and the control of impulsive and emotional behaviour impaired in ADHD. Phonological deficits are associated with learning problems in literacy and maths, and impairments in nonverbal and executive abilities with mathematical learning difficulties. The comorbid condition of ADHD combined with learning difficulties reflects independent deficits in the cognitive dimensions critical for learning and in the control of impulsive and emotional behaviour.

animal behavior and cognition